Fertilizarea in vitro: diagnostic de preintampinare, indicatiile procedurii la potentialii parinti cu tulburari genetice

In vitro fertilization: pre-indication diagnosis, procedure indications to potential parents with genetic disorders

Many families want a child, but for some it remains just a dream. Thanks to the in vitro fertilization procedure, families have a real chance to realize the dream of having children.

Every day we have findings in the field of in vitro fertilization. The technology of advanced technology has also left its mark on the development of this method, and success has more and more options to manifest itself. Moreover, the risks and the rate of failure fall greatly. Dr Sahin Zeteroglu, associate professor, gynecologist and obstetrician at Acıbadem Bursa Hospital, told us more about how advanced in vitro fertilization methods have been told.

Intracytoplasmic sperm injection selected morphologically

The IMSI procedure is applied to the treatment of patients who choose to in vitro fertilization due to infertility in men. Through IMSI we have the ability to better synthesize sperm structures, and anomalies are detected even in a sperm that looks healthy. Currently, sperm selection uses a microscope that can provide images clarity 6-8000 times. The figure is quite impressive compared to the previous microscope that offered image sizes from 300 to 350 times.

The Micro TESE method

Initially, the procedure called TESE was applied in which the open testis opened by mapping was subjected to tissue extraction. To avoid the occurrence of complications, it is advisable to maintain low levels of extracted tissue. Thus, no living tissue was visible, and the sperm existence was believed to be null.

Now we have a new method, Micro TESE. Each area is scanned right under the microscope. The testicle is mapped and offers the chance to receive a living semen. This increases hopes of having sperm and reduces the chances of creating some discomfort to the patient.

Transfer on day 5

As a rule, embryo transfer was performed on the third day. Thanks to state-of-the-art laboratory technologies, the transfer is now on the fifth day. According to the mandatory embryo transfer policy, it is essential to select the best embryo. Until the third day, there are 10 embryos, and until day five, there are about 3-4 embryos. Transfer this day increases your chance of selecting the best quality embryo.

Genetic Preimplantation Diagnosis (PDG)

There are a number of patients who need a genetic consultation over in vitro fertilization. This means that the adult is subjected to blood sampling, and then the genetic map of the patient is formed within 15 days. However, genetic testing for the in vitro fertilization procedure means collecting cells from the embryo and creating that map until it is placed in the pantec. As a rule, this procedure uses couples and patients with genetic problems or the risk category for repeated pregnancy loss. The PDG procedure is performed if one of the partners has a genetic anomaly, which prevents the child from conceiving. Another reason to resort to this test is recommended if there is a risk that the future infant will be born with certain serious health problems.

Genetic pre-implantation diagnosis gives the embryo's chance to be checked against parental illnesses. PDG also allows the selection of normal embryos, and then their transfer.

Assisted hatching

The embryo wall is thinned by the laser. The embryo is attached to an area on the uterus wall that is prepared early by the thinning method. This increases the chances of implantation.

Method Metabolic

At the moment research is being done on a new method, called metabolic. Just like an adult, the embryo takes the nutrients from the environment and eliminates others. By the metabolic method the embryo with faster metabolism is more likely to be chosen by examining the elements it eliminates. However, confirmed information such as the accelerated metabolism embryo is better than the rest, it still does not exist. For this reason, this method was not yet approved.

Who are the patients of in vitro fertilization?

Patients who can use the in vitro fertilization procedure are couples in which the male has a low sperm count or has no other choice and no other means of conception by natural methods. Also, the in vitro fertilization procedure may involve patients experiencing low ovulation or for whom infertility can not be explained. There are also methods that can be used before taking this procedure.

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